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Olihile Sebolai

The Lipid Composition of the Yeast Genus Saccharomycopsis Schionning


A taxonomic and bioprospective study
2010. 140 S.
Verlag/Jahr: VDM VERLAG DR. MÜLLER 2010
ISBN: 3-639-23786-2 (3639237862)
Neue ISBN: 978-3-639-23786-3 (9783639237863)

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In this study, the construction of a forecasting model, using intracellular fatty acid composition as indicator, was attempted to assist in the search for yeasts capable of producing 3-hydroxy oxylipins. In order to achieve this, it was first attempted to establish a database mapping the distribution of fatty acids (FAs) associated with the neutral-, glyco- and phospholipid fractions of the 10 species representing the genus Saccharomycopsis. It was possible to identify nine of the 10 species. Although it was possible to differentiate between most species using this phenotypic character, these FAs could not be used to predict what kind of 3-OH oxylipins these species are capable of producing. As observed in S. capsularis and S. javanensis both produced 3-OH 9:1, fatty acids with uneven carbon atoms which may serve as precursors could not be detected in the neutral-, glyco- or phospho-lipid fractions.
Olihile Moses Sebolai is a staff member of the University of the Free State. He obtained his doctoral degree from the Department of Microbial, Biochemical and Food Biotechnology at the University of the Free State. His research interest is understanding the role of oxylipins in the pathogenesis of Cryptococcus neoformans.