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Serum globulin, total antioxidant status and selenium concentration decreased significantly while AST, T3, T4, homocysteine, total oxidant status, MDA, K, Ca, Zn did increase during 1st trimester of pregnancy. Serum cholesterol, triglyceride, AST, T3, T4, homocysteine, total oxidant status, MDA, Ca, Zn were significantly higher while serum total proteins, albumin, antioxidant status, Na, K and Se did decrease significantly during 2nd trimester. A significant high level of body temperature, triglyceride, LDL-cholesterol, AST, T3, homocysteine, total oxidant status, MDA, Ca and zinc concentration while lower concentration of serum proteins, albumin, antioxidant status, Na, Fe and Se concentration was observed in women at the end of the pregnancy. Pearson correlation was determined to observe the relationship of homocysteine and DNA damage with the clinical biochemical profiles of pregnant women.

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Dr. Shazia Anwer Bukhari is currently working as an Assistant Professor in the Department of Chemistry, Government College University, Faisalabad, Pakistan. She had teaching and research experience of seven years, published 2 books and over 11 research papers and abstracts in internationally reputed journals.

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