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Johannes Baumgart
The Hair Bundle
Fluid-Structure Interaction in the Inner Ear
2011. 148 S. 220 mm
Verlag/Jahr: SÜDWESTDEUTSCHER VERLAG FÜR HOCHSCHULSCHRIFTEN 2011
ISBN: 3-8381-2727-7 (3838127277)
Neue ISBN: 978-3-8381-2727-9 (9783838127279)
Preis und Lieferzeit: Bitte klicken
In this work a novel approach is introduced to analyze the mechanics of the fluid-structure interaction problem in the inner ear. Because the motions during normal mechanotransduction are much smaller than the geometrical scales, a unified linear system of equations describes with sufficient accuracy the behavior of the liquid and solid in terms of a displacement variable. The finite-element method is employed to solve this system of partial differential equations. Based on data from the hair bundle of the bullfrog´s sacculus, a detailed model is constructed that resolves simultaneously the interaction with the surrounding liquid as well as the coupling liquid in the narrow gaps between the individual stereocilia. The experimental data are from high-resolution interferometric measurements at physiologically relevant amplitudes in the range from a fraction of a nanometer to several tens of nanometers and over a broad range of frequencies from one millihertz to hundred kilohertz.
He received the Dipl.-Ing. and Dr.-Ing. degrees in mechanical engineering from the Technische Universität Dresden, in 2003 and 2010, respectively. In 2004 he received a Diploma in Aeronautics and Aerospace from the von Karman Institute for Fluid Dynamics. He is now with the Max Planck Institute for the Physics of Complex Systems in Dresden.