---

Practical Three-Way Calibration is an introductory-level guide to the complex field of analytical calibration with three-way instrumental data. With minimal use of mathematical/statistical expressions, it walks the reader through the analytical methodologies with helpful images and step-by-step explanations. Unlike other books on the subject, there is no need for prior programming experience and no need to learn programming languages. Easy-to-use graphical interfaces and intuitive descriptions of mathematical and statistical concepts make three-way calibration methodologies accessible to analytical chemists and scientists in a wide range of disciplines in industry and academia.

Numerous detailed examples of slowly increasing complexity
Exposure to several different data sets and techniques through figures and diagrams
Computer program screenshots for easy learning without prior knowledge of programming languages
Minimal use of mathematical/statistical expressions

---

Foreword
1. Calibration Scenarios
2. Data Properties
3. Experimental Three-Way/Second-Order Data
4. The Mvc2 Software
5. Parallel Factor Analysis: Trilinear Data
6. Analytical Figures of Merit
7. Parallel Factor Analysis: Non-Trilinear Data of Type 1
8. Multivariate Curve Resolution-Alternating Least-Squares
9. Partial Least-Squares with Residual Bilinearization
10. Three-Way/Second-Order Standard Addition
11. Third-Order/Four-Way Calibration and Beyond
12. Application Example: Parafac
13. Application Example: Mcr-Als
14. Application Example: U-Pls/Rbl
15. Solutions to Homework

---

"...will enrich your analytical chemistry perspectives, help you better plan and process your experimental data..." --Chemistry in Australia

"...a very useful source for anyone who wants to acquire a basic knowledge of three-way calibration, and is particularly useful for applied researchers." -- Journal of Chemometrics

---

Olivieri, Alejandro
Alejandro Olivieri is an analytical chemist/chemometrician with extensive experience in the application of multi-way calibration methods to analytical determinations in complex samples, and in the development of multi-way calibration algorithms. He has published approximately 200 scientific papers in mainstream journals in the last 15 years specifically devoted to analytical chemistry and multi-way calibration. Olivieri is a Fellow of the John Simon Guggenheim Memorial Foundation (2000-2002) and a Member of the Board of Editors of Talanta (Elsevier).

Escandar, Graciela M.
Graciela Escandar was born in Rosario, Argentina. She obtained her B.Sc. in Biochemistry in 1983 and her Ph.D. in 1992, both from the Faculty of Biochemical and Pharmaceutical Sciences, University of Rosario, where she is now Associate Pofessor in the Department of Analytical Chemistry, and fellow of the National Research Council of Argentina (CONICET). She has published about 100 scientific papers in international journals and book chapters and supervised six Ph.D. Theses. Her research focuses on the development of new luminescent methodologies coupled to multi-way calibration of analytes of environmental and pharmaceutical interest.

---