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Bridging the conceptual gulf between biology, mathematics and information technology, this volume aims for interdisciplinary appeal and introduces some of the key methods and technologies in systems biology, assessing their effectiveness through case studies.

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This book is intended as a communication platform to bridge the cultural, conceptual, and technological gap among the key systems biology disciplines of biology, mathematics, and information technology. To support this goal, contributors were asked to adopts an approach that appeals to audiences from different backgrounds.

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Preface.- Effects of Protein Quality Control Machinery on Protein Homeostasis.- Metabolic Network Dynamics: Properties and Principles.- A Deterministic, Mathematical Model for Hormonal Control of the Menstrual Cycle.- Modelling Transport Processes and their Implications for Chemical Disposition and Action.- Systems Biology of Tuberculosis: Insights for Drug Discovery.- Qualitative Analysis of Genetic Regulatory Networks in Bacteria.- Modelling Antibiotic Resistance in Bacterial Colonies Using Agent-Based Approach.- Modelling the Spatial Pattern Forming Modules in Mitotic Spindle Assembly.- Cell-Centred Modelling of Tissue Behaviour.- Interaction-Based Simulations for Integrative Spatial Systems Biology.- Glossary.- Index.

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