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The development of the brain and nervous system is shaped not just by a genetic program, but also by the effects of multiple environmental stimuli. There are currently no book-length treatments of perinatal neurodevelopment. The proposed book seeks to fill this gap by presenting a collection of chapters from leading experts in the field. It is intended to be comprehensive and will cover all aspects of neurodevelopmental programming in lab animals and in human subjects. The third section of the book will look at ways of translating insights we have garnered from animal studies to human and clinical studies. The primary audience for this work is basic researchers interested in the effects of perinatal imprinting on the development of the nervous system and associated diseases.

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1. Changes Induced by Prenatal Stress in Behavior and Brain Morphology. Can they be Prevented or Reversed?
Marta Weinstock

2. Sleep in Prenatally Restraint Stressed Rats, a Model of Anxious Depression
Jérôme Mairesse, Gilles Van Camp, Eleonora Gatta, Jordan Marrocco, Marie-Line Reynaert, Michol Consolazione, Sara Morley-Fletcher, Ferdinando Nicoletti, Stefania Maccari

3. Hormonal Modulation of Catecholaminergic Neurotransmission in a Prenatal Stress Model María Eugenia Pallarés, Marta C. Antonelli

4. Involvement of Nitric Oxide, Neurotrophins and HPA Axis in Neurobehavioral Alterations Induced by Prenatal Stress
Damian G. Maur, Cecilia G. Pascuan, Ana M. Genaro, Maria A. Zorrilla-Zubilete

5. Prenatal Stress and Adult Drug-seeking Behavior: Interactions with Genes and Relation to Non-drug Related Behavior
Tod E. Kippin, Joannalee C. Campbell, Kyle Ploense, Chris P. Knight, Jared Bagley

6. A Self-medication Hypothesis for Increased Vulnerability to Drug Abuse in Prenatally Restraint Stressed Rats
Marie-Line Reynaert, Jordan Marrocco, Eleonora Gatta, Jérôme Mairesse, Gilles Van Camp, Francesca Fagioli, Stefania Maccari, Ferdinando Nicoletti, Sara Morley-Fletcher

7. How Postnatal Insults May Program Development - Studies in Animal Models Carla Dalmaz, Cristie Noschang, Rachel Krolow, Charlis Raineki, Aldo B. Lucion

8. Perinatal Positive and Negative Influences on the Early Neurobehavioral Reflex and Motor Development
Gabor Horvath, Dora Reglödi, Jozsef Farkas, Gyongyver Vadasz, Barbara Mammel, Timea Kvarik, Greta Bodzai, Blanka Kiss-Illes, Dorottya Farkas, Attila Matkovits, Sridharan Manavalan, Balazs Gaszner, Andrea Tamas, Peter Kiss

9. Short and Long-term Consequences of Perinatal Asphyxia: Looking for Neuroprotective Strategies
M. Herrera-Marschitz, T. Neira-Pe¤a, E. Rojas-Mancilla, P. Morales, D. Bustamante, L. Leyton, P. Gebicke-Haerter

10. Affective, Cognitive and Motivational Processes of Maternal Care
Mariana Pereira, Annabel Ferreira

11. Role of Sensory, Social and Hormonal Signals from the Mother on the Development of Offspring
Angel I. Melo

12. Retrospective Studies
Patrícia Pelufo Silveira, Gisele Gus Manfro

13. Prenatal Stress and its Effects on the Fetus and the Child; Possible Underlying Biological Mechanisms
Vivette Glover

14. Using Natural Disasters to Study Prenatal Maternal Stress in Humans
Suzanne King, David P. Laplante

15. Early Life Influences on Cognition, Behavior and Emotion in Humans: From Birth to Age 20
Bea R.H. Van den Bergh, Eva M. Loomans, Maarten Mennes

16. Perinatal Programming of Neurodevelopment. Epigenetic Mechanisms and the Prenatal Shaping of the Brain
Paula A. Desplats

17. Epigenetic Mechanisms of Perinatal Programming: Translational Approaches from Rodent to Human and Back
Patrick O. McGowan

18. Perinatal Administration of Aromatase Inhibitors in Rodents as Animal Models of Human Male Homosexuality: Similarities and Differences
Sandra Olvera-Hernández, Alonso Fernández-Guasti

19. Impact of the Perinatal Environment on Child Development: Implications for Prevention Policies
Fran‡oise Molenat

20. Perinatal Programming Prevention Measures
A. Miguel Larguía, María Aurelia González, Néstor Alejandro Dinerstein,
Constanza Soto Conti

21. Pregnancy Outcomes after a Maternity Intervention for Stressful EmotionS (PROMISES): A Randomised Controlled Trial
Huibert Burger, Claudi L.H. Bockting, Chantal Beijers, Tjitte Verbeek, A. Dennis Stant, Johan Ormel, Ronald P. Stolk, Peter de Jonge, Mari‰lle G. van Pampus, Judith Meijer

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