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This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.

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FERMENTATION & DOWNSTREAM PROCESSING TECHNOLOGIES
Process development tools for fermentations under extreme conditions (ProTool)
Development of fully automated integrated bioprocesses in an industrial compatible pilot plant for the production of heterologous enzymes in yeast
Application of tailor made porous adsorbents in enzymatic processes
In-situ video microscopy for investigation and optimization of protein crystallization in downstream processing
Innovative plasma technology for enzyme immobilization
New membrane adsorber technology for downstream processing in enzyme production
BIOCATALYSIS & BIOTECHNOLOGICAL PRODUCTION PROZESSES
Biocatalysis in high viscous media
COMPASITES: Computer assisted analysis of active centers in proteins
Kongeneric lipases with improved catalytic activity and substrate accessibility
Biocatalytic exploitation of flavonoids
New Bacillus expression systems
First SeSaM-mutagenesis kit for evolutionary biocatalyst design
Development of a probiotic preserving agent for industrial applications
Development of a biotechnological production process for non-natural cyclopeptides - BioPEP
Biocatalytic exploitation of flavor enhancing aroma compounds
STABLE ENZYMES
Enzymatic oxidation systems food and technical applications
Preparation of new perhydrolases: Simultaneous enhancement of specific activity of perhydrolases and reduction of hydrolysis activity
Nucleases and proteases exhibiting improved properties for molecular preanalytics
Stable enzymes for the conversion of high value and uncommon substrates

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