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The first book to place recent academic developments within the context of real life industrial applications, this is a timely overview of the field of aerobic oxidation reactions in the liquid phase that also illuminates the key challenges that lie ahead.
As such, it covers both homogeneous as well as heterogeneous chemocatalysis and biocatalysis, along with examples taken from various industries: bulk chemicals and monomers, specialty chemicals, flavors and fragrances, vitamins, and pharmaceuticals. One chapter is devoted to reactor concepts and engineering aspects of these methods, while another deals with the relevance of aerobic oxidation catalysis for the conversion of renewable feedstock.
With chapters written by a team of academic and industrial researchers, this is a valuable reference for synthetic and catalytic chemists at universities as well as those working in the pharmaceutical and fine chemical industries seeking a better understanding of these reactions and how to design large scale processes based on this technology.

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Preface
List of Contributors
PART I RADICAL CHAIN AEROBIC OXIDATION
1 Overview of Radical Chain Oxidation Chemistry
2 Noncatalyzed Radical Chain Oxidation: Cumene Hydroperoxide
3 Cyclohexane Oxidation: History of Transition from Catalyzed to Noncatalyzed
4 Chemistry and Mechanism of Oxidation of para-Xylene to Terephthalic Acid Using Co-Mn-Br Catalyst
PART II Cu-CATALYZED AEROBIC OXIDATION
5 Cu-Catalyzed Aerobic Oxidation: Overview and New Developments
6 Copper-Catalyzed Aerobic Alcohol Oxidation
7 Phenol Oxidations
PART III Pd-CATALYZED AEROBIC OXIDATION
8 Pd-Catalyzed Aerobic Oxidation Reactions: Industrial Applications and New Developments
9 Acetaldehyde from Ethylene and Related Wacker-Type Reactions
10 1,4-Butanediol from 1,3-Butadiene
11 Mitsubishi Chemicals Liquid Phase Palladium-Catalyzed Oxidation Technology: Oxidation of Cyclohexene, Acrolein, and Methyl Acrylate to Useful Industrial Chemicals
12 Oxidative Carbonylation: Diphenyl Carbonate
13 Aerobic Oxidative Esterification of Aldehydes with Alcohols: The Evolution from Pd-Pb Intermetallic Catalysts to Au-NiOx Nanoparticle Catalysts for the Production of Methyl Methacrylate
PART IV ORGANOCATALYTIC AEROBIC OXIDATION
14 Quinones in Hydrogen Peroxide Synthesis and Catalytic Aerobic Oxidation Reactions
15 NOx Cocatalysts for Aerobic Oxidation Reactions: Application to Alcohol Oxidation
16 N-Hydroxyphthalimide (NHPI)-Organocatalyzed Aerobic Oxidations: Advantages, Limits, and Industrial Perspectives
17 Carbon Materials as Nonmetal Catalysts for Aerobic Oxidations: The Industrial Glyphosate Process and New Developments
PART V BIOCATALYTIC AEROBIC OXIDATION
18 Enzyme Catalysis: Exploiting Biocatalysis and Aerobic Oxidations for High-Volume and High-Value Pharmaceutical Syntheses
PART VI OXIDATIVE CONVERSION OF RENEWABLE FEEDSTOCKS
19 From Terephthalic Acid to 2,5-Furandicarboxylic Acid: An Industrial Perspective
20 Azelaic Acid from Vegetable Feedstock via Oxidative Cleavage with Ozone or Oxygen
21 Oxidative Conversion of Renewable Feedstock: Carbohydrate Oxidation
PART VII AEROBIC OXIDATION WITH SINGLET OXYGEN
22 Industrial Prospects for the Chemical and Photochemical Singlet Oxygenation of Organic Compounds
PART VIII REACTOR CONCEPTS FOR LIQUID PHASE AEROBIC OXIDATION
23 Reactor Concepts for Aerobic Liquid Phase Oxidation: Microreactors and Tube Reactors
Index

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