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Following the successful and proven concept used in "Bioactive Heterocyclic Compound Classes" by the same editors, this book is the first to present approved pharmaceutical and agrochemical compounds classified by their carboxylic acid functionality in one handy volume.
Each of the around 40 chapters describes one or two typical syntheses of a specific compound class and provides concise information on the history of development, mode of action, biological activity and field of application, as well as structure-activity relationships. In addition, similarities and differences between pharmaceuticals and agrochemicals are discussed in the introduction.
Written by a team of experts in the field, this is a useful reference for researchers in academia and chemical or pharmaceutical companies working in the field of total synthesis and natural product chemistry, drug development, and crop protection research.

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1. Introduction: Different Roles of Carboxylic Acid Functions in Pharmaceutical and Agrochemical Active Ingredients
PART I: PHARMACEUTICALS
2. Angiotensin II Receptor Antagonistic Acids in Cardiovascular Disease
3. Anti-inflammatory Corticosteroid Esters
4. Non-steroidal Anti-Inflammatory Drugs (NSAIDs)
5. Anticholinergic Muscarinic Receptor Antagonist Esters
6. Oxazolidinone Amide Antibiotics
7. Prostaglandine Analog Esters and Amides for the Treatment of Glaucoma
8. 5a-Reductase Inhibiting Amides
9. Analgesic and Anesthetic Amides
10. Fibrate Acids and Esters in the Treatment of Hyperlipidemia
11. Dipeptidyl Peptidase-4 (DPP-4) Inhibiting Amides
12. NS5B Polymerase Inhibiting Esters (Sovaldi)
13. Dimethyl Fumarate for the Treatment of Multiple Sclerosis
14. Acids for the Treatment of Neuropathic Pain, Anxiety Disorder, and Fibromyalgia (Pregabalin, Lyrica)
15. Factor Xa Inhibiting Amides (Rivaroxaban, Xarelto)
16. Thrombin Inhibiting Esters and Acids
17. Neuraminidase Inhibiting Esters and Acids
18. Carboxylic Acids as Antihistamines
19. Norepinephrine-Dopamine Reuptake Inhibiting Esters (Ndris)
20. Statin HMG Coa Reductase Inhibiting Acids as Hypolipidemic Agents
21. Tyrosine Kinase Inhibiting Amides (Ibrutinib)
22. Chemotherapeutic Acids (Pemetrexed)
23. Platelet Inhibiting Esters for the Reduction of Thrombotic Cardiovascular Events (Prasugrel)
24. TAAR1 Agonist Amides for the Treatment of ADHD (Lisdexamfetamine)
PART II: AGROCHEMICALS
HERBICIDES
25. Amino Acids as Non-Selective Herbicides
26. Herbicidal Esters Inhibiting Protoporphyrinogen Oxidase
27. Herbicidal Chloroacetamides
28. Herbicidal ALS-Inhibiting Imidazolinone Carboxylic Acids
29. Herbicidal Benzoic Acids and Phenoxyacetic Acids as Synthetic Auxins
30. Herbicidal ALS-Inhibiting Sulfonylureas
31. Herbicidal Aryloxyphenoxypropionates (FOPs) Inhibiting Acetyl-Coa Carboxylase
FUNGICIDES
32. Fungicidal Complex III Inhibiting Strobilurin Esters and Amides
33. Fungicidal Succinate Dehydrogenase Inhibiting Carboxamides
34. Fungicidal RNA Polymerase Inhibiting Phenylamides
35. Fungicidal Carboxylic Acid Amide Fungicides Inhibiting Cellulose Synthase
36. Melanin Biosynthesis Inhibiting Amides as Rice Fungicides
INSECTICIDES
37. Insecticidal Pyrethroid Esters
38. Insecticidal Juvenile Hormone Analog Esters
39. Chitin Biosynthesis Inhibiting Benzoylureas
40. Ecdyson Receptor Agonistic Diacylhydrazine Insecticides
41. Acetyl Coa Esterase Inhibiting Tetramic and Tetronic Acid Procide Esters and Carbonates
42. Ryanodine Receptor Modulating Diamides

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