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Anne Maass
7T high-resolution fMRI of the human hippocampal-entorhinal circuitry
2016. 184 S. 220 mm
Verlag/Jahr: SÜDWESTDEUTSCHER VERLAG FÜR HOCHSCHULSCHRIFTEN 2016
ISBN: 3-8381-5226-3 (3838152263)
Neue ISBN: 978-3-8381-5226-4 (9783838152264)
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The hippocampus and the entorhinal cortex build a neural circuitry within the medial temporal lobe that is critical for the formation of long-term memory. Dysfunction of specific hippocampal and entorhinal subregions has been implicated in cognitive aging and early stages of Alzheimer´s disease. The current work aimed to investigate the functional anatomy and exercise-related plasticity of the human hippocampal-entorhinal circuitry by means of 7 Tesla ultra-high field functional and structural magnetic resonance imaging (MRI). The current work highlights the potential of 7T high-resolution imaging for studying memory function of the human medial temporal lobe but also points to the challenges that high-field MRI poses.
- 1985: born in Gardelegen, Germany- grown up in Magdeburg- 2008: BSc in Biochemistry, University Potsdam- 2011: MSc in Integrative Neuroscience, University Magdeburg- 2015: PhD in Neuroscience, Institute of Cognitive Neurology and Dementia Research, Magdeburg(Prof. Emrah Düzel)- since 2015: PostDoc in Berkeleley, USA