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Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed.

Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration.

Contains systematic coverage on how both healthy and injured tendons and ligaments work
Includes coverage of repair and regeneration strategies for tendons and ligaments
Presents an Interdisciplinary analysis on the topic

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Part One: Fundamentals and biomechanics of tendons and ligaments 1. Structure and function of tendon and ligament tissues 2. Biomechanical properties of tendons and ligaments in humans and animals 3. Mechanobiology of tendons and ligaments 4. Experimental methods for measuring tendon and ligament biomechanics 5. Imaging of tendons and ligaments in animal models

Part Two: Repair and regeneration of tendons and ligaments 6. Autograft, allograft, and xenograft scaffolds for tendon and ligament repair: Materials and biomechanics 7. Collagen for tendon and ligament repair: Preparations and biomechanics 8. Synthetic polymer scaffolds for tendon and ligament repair: Materials and biomechanics 9. Cell therapies for tendons and ligament repair 10. In vitro-in vivo biomechanical performance of tissue-engineered constructs for tendon and ligament repair 11. Role of cellular response in the healing process of tendons and ligaments 12. Evolving treatments and emerging strategies for tendon and ligament reconstruction

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Buschmann, Johanna
Dr. Johanna Buschmann was educated as a chemist at the ETH Zurich. She is the leader of the research laboratories at the Department of Plastic and Hand Surgery at the University Hospital Zurich since 2008. Johanna is an active member of the Swiss Bone and Mineral Society and the Swiss Society for Biomaterials and Regenerative Medicine. She has reviewed articles for journals such as Biomaterials, Critical Reviews in Biomedical Engineering and Cytotherapy. Her main research activities lie in the field of tendon regeneration, tissue engineering and stem cell therapy.

Meier Bürgisser, Gabriella
Gabriella Meier Bürgisser was educated as a biologist at the ETH Zurich, Switzerland (Master of Science). She is working at the University Hospital Zurich in the Clinic for Plastic Surgery and Hand Surgery. Her main research lies in the field of tendon repair.

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