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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today´s destructive diseases.
To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer´s, Parkinson´s and Huntington´s disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine.
With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.

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Neuroprotective natural products: An overview
Neuroprotective agents: An overview on the general modes of action
Beneficial upshots of naturally occurring antioxidant compounds against neurological disorders
Natural neuroprotectives for the management of Parkinson´s Disease
Neuroprotective effect of Ayurvedic preparations and natural products on Parkinson´s disease
Lipid peroxidation and mitochondrial dysfunction in Alzheimer´s and Parkinson´s diseases: Role of natural products as cytoprotective agents
Anti-Alzheimer´s agents from sea
Natural products against Huntington´s disease: Implications of neurotoxic animal models and trangenics in preclinical studies
Possible role of neuroprotectants and natural products in epilepsy: Clinical aspects and mode of action
Neuroprotective effects of flavonoids in epilepsy
The role of noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors in treatment-resistant depression
Safety and efficacy of Ashwagandha (Withania somnifera)Cannabinoids: A group of promising neuroprotective agents

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After receiving his Ph.D. in 1997 at Visva-Bharati University (India), Goutam Brahmachari joined his alma mater and currently holds the position of a full professor of chemistry since 2011. Research interests of his group include green chemistry, organic synthesis and medicinal chemistry of natural products, as well as artificial compounds. With more than 18 years of experience in both teaching and research, he has produced nearly 160 scientific publications including original research papers, review articles, books and invited book chapters in the fields of natural products and green chemistry. He has authored/edited 18 books and more than 30 book chapters so far published by internationally reputed major presses. He is the Series Editor of the Book Series ´Natural Product Drug Discovery´.

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