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The second edition of this work continues to address the intimate pathophysiologic relationship between hypertension and stroke. The editors and authors clearly and concisely synthesize our developing knowledge of this relationship and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of other cerebrovascular risk factors. In addition to prescriptive measures for first stroke prevention, the book illuminates current regimens for care immediately after acute stroke and for the prevention of recurrent stroke. This latest edition also features extensively updated chapters from the previous edition, as well as new chapters on the effects of hypertension and stroke on the cerebral vasculature, blood pressure management in subarachnoid hemorrhage, and blood pressure variability, antihypertensive therapy, and stroke risk.
Written by experts in the field, Hypertension and Stroke: Pathophysiology and Management, Second Edition is of great utility for specialists in neurology and cardiovascular medicine and a valuable practical resource for all physicians caring for older adults and hypertensive patients.

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I: Blood Pressure and Hypertension as Antecedents of Stroke
1. Blood Pressure: Definition, Diagnosis, and Management Raymond R. Townsend and Susan P. Steigerwalt
2. The Link Between Hypertension and Stroke: Summary of Observational Epidemiological Studies Dilip K. Pandey, Noha Aljehani, and Youji Soga
3. Blood Pressure Control and Primary Prevention of Stroke: Summary of Clinical Trial Data William J. Elliott
II: Mechanisms of Hypertension and Hypertension-Related Stroke
4. Mechanisms Underlying Essential Hypertension: Neurogenic and Non-neurogenic Scott H. Carlson, Sean Stocker, and J. Michael Wyss
5. The Effects of Hypertension and Stroke on the Cerebral Vasculature Anne M. Dorrance
6. Pathophysiology and Mechanisms Whereby Hypertension May Cause Stroke Beom Joon Kim, Hee-Joon Bae, and Lawrence K. S. Wong
III: Management of Blood Pressure for First Stroke Prevention, Immediately after Acute Stroke, and for Recurrent Stroke Prevention
7. Cardiovascular Risk Assessment, Summary of Guidelines for the Management of Hypertension and a Critical Appraisal of the 2014 Expert Panel of the National Institutes of Health Report Luke J. Laffin and George L. Bakris
8. Acute Blood Pressure Management After Ischemic Stroke J. Dedrick Jordan and William J. Powers
9. Hypertensive Encephalopathy, Posterior Reversible Encephalopathy Syndrome, and Eclampsia Karen Orjuela and Sean D. Ruland
10. Acute Blood Pressure Management After Intracerebral Hemorrhage Venkatesh Aiyagari
11. Blood Pressure Management in Subarachnoid Hemorrhage: The Role of Blood Pressure Manipulation in Prevention of Rebleeding and the Management of Vasospasm Zakraus K. Mahdavi, Claudia A. Perez, and Michael A. Rubin
12. Recurrent Stroke Prevention I: Diuretic and Angiotensin-Converting Enzyme Inhibitors (ACEIs) - The PROGRESS Trial Thomas K. A. Linden and Geoffrey A. Donnan
13. Blood Pressure Variability, Antihypertensive Therapy and Stroke Risk Muhammad U. Farooq, Jiangyong Min, Lawrence K. S. Wong, and Philip B. Gorelick
14. A Review of Antihypertensive Drugs and Choosing the Right Antihypertensive for Recurrent Stroke Prevention Domenic A. Sica
IV: Mechanisms and Sequelae of Elevated Blood Pressure on Brain Function and Cognition
15. Vascular Cognitive Impairment and Alzheimer Disease: Are These Disorders Linked to Hypertension and Other Cardiovascular Risk Factors? Fernando D. Testai and Philip B. Gorelick
16. Hypertension, Cerebral Small Vessel Disease, and Cognitive Function David L. Nyenhuis
17. Cerebral Microbleeds, Small-Vessel Disease of the Brain, Hypertension and Cognition Anand Viswanathan, Hugues Chabriat, and Steven M. Greenberg
18. Neuroimaging of Hypertension and Related Cerebral Pathology Alejandro Magadán

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