---

A much-needed summary of the importance, synthesis and applications of metal nanoparticles in pharmaceutical sciences, with a focus on gold, silver, copper and platinum nanoparticles. After a brief introduction to the history of metal complexes in medicine and fundamentals of nanotechnology, the chapters continue to describe different methods for preparation of metal nanoparticles. This section is followed by representative presentations of current biomedical applications, such as drug delivery, chemotherapy, and diagnostic imaging.
Aimed at stimulating further research in this field, the book serves as an reference guide for academics and professionals working in the field of chemistry and nanotechnology.

---

1) Introduction: History of Metal Complexes, Nanotechnology, Nanoparticles
2) Methods for Preparation of Metal Nanoparticles
3) Metal Nanoparticles as Therapeutic Agents: A Paradigm-Shift in Medicine
4) Nanoparticles for Imaging
5) Soft-Oxometalates: A New State of Oxometalates and their Potential Applications as Nanomotors
6) Medicinal Application of Metal Nanoparticles and Complexes
7) Metal Nanoparticles in Nanomedicine: Advantages and Scopes
8) Metal Nanoparticles as Anticancer Agents
9) Noble Metal Nanoparticles and their Antimicrobial Properties
10) Metal Nanoparticles and their Toxicity

---

Sreekanth Thota is a Visiting Researcher at the Center for Technological Development in Health, Funda‡Æo Oswaldo Cruz - Fiocruz in Rio de Janeiro, Brazil. He studied Pharmaceutical Chemistry at Kakatiya University (India) and Rajiv Gandhi University of Health Sciences (Bangalore, India) and obtained his Ph.D from Jawaharlal Nehru Technological University Hyderabad (India) in 2011. He then did postdoctoral work at Colorado State University, USA. He received the 2013 CAPES-Fiocruz, Visiting Researcher award and has published over 40 articles in peer-reviewed journals. His research interest is focused on the drug discovery, medicinal chemistry, fundamental chemistry and biochemistry of ruthenium and other transition metal ions leading to applications in medicine. Debbie C. Crans is Professor of Organic and Inorganic Chemistry and in the Cell and Molecular Biology Program at Colorado State University, Fort Collins, USA. She obtained her Ph.D. in Chemistry from Harvard University with George M. Whitesides, USA, in 1985. She did a postdoctoral fellowship with Orville L. Chapman and Paul D. Boyer at UCLA in 1986. Her research interests lie in biological chemistry with expertise in metals in medicine and coordination chemistry with a focus on transition metals such as vanadium and platinum and interests in membrane model systems and hydrophobic compounds and lipids such as menaquinone. She received the Vanadis Award in 2004 and in the 2015 Cope Scholar Award. She has published over 190 articles in peer-reviewed journals.

---