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Antonio Subtil

Diagnosis of Cutaneous Lymphoid Infiltrates


A Visual Approach to Differential Diagnosis and Knowledge Gaps
1st ed. 2019. 2019. xiv, 333 S. 277 Farbabb., 277 Farbtabellen. 254 mm
Verlag/Jahr: SPRINGER, BERLIN; SPRINGER INTERNATIONAL PUBLISHING 2019
ISBN: 3-03-011652-2 (3030116522)
Neue ISBN: 978-3-03-011652-1 (9783030116521)

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This volume is the first of its kind to emphasize the visual approach in the diagnosis of cutaneous lymphoid infiltrates. Written and designed in an accessible yet highly detailed format by an expert in the field, this book bridges the knowledge gaps so often found when dealing with skin lymphomas. Complete with more than two hundred high quality images and illustrations, Diagnosis of Cutaneous Lymphoid Infiltrates offers pearls and pitfalls as well as differential diagnoses. Additionally, images are explained and decoded with the use of illustrations and analogies, proving to be an invaluable resource for pathologists, dermatologists, dermatopathologists, hematopathologists, and residents and fellows in these fields.
Part I: The Basics.- Clinical Pathological Correlation.- Skin Biopsy Evaluation.- Lymphocyte Morphology.- Lymphoid Follicle Morphology and Components.- Reactive Versus Neoplastic Lymphoid Follicles.- Extrafollicular Localization of Germinal Center Cells.- Part II: Histomorphologic Differential Diagnosis (DDx).- DDx of Epidermotropism.- DDx of Ulceration.- DDx of Perifollicular Accentuation.- DDx of Eosinophil-Rich Infiltrate.- DDx of Lymphoid Follicle Formation.- DDx of Angiocentrism.- DDx of Pannicular-based Infiltrate.- DDx of Large Cell Infiltrate.- Part III: Special Techniques.- Basic Immunohistochemistry Panels.- CD8-Positive Cutaneous Infiltrates.- Differential Diagnoses of CD30 Expression.- Differential Diagnoses of CD56.- EBV-positive Cutaneous Infiltrates.- Differential Diagnoses of BCL2-positive follicles.- Part IV: Diagnostic Entities.- Secondary Cutaneous Invovlement by Systemic/Nodal Lymphomas.- Classic Mycosis Fungoides (MF).- Folliculotropic Mycosis Fungoides (FMF).- Pagetoid Reticulosis.- Granulomatous Slack Skin.- Sezary Syndrome.- Primary Cutaneous CD30+ Lymphoproliferative Disorders, Primary Cutaneous Anaplastic Large Cell Lymphoma.- Primary Cutaneous CD30+ Lymphoproliferative Disorders, Lymphomatoid Papulosis.- Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoproliferate Disorder.- Subcutaneous Panniculitis-like T-cell Lymphoma (alpha-beta).- Cutaneous Gamma-Delta T-cell Lymphoma.- Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma.- Extranodal NK/T-cell Lymphoma, Nasal Type.- Hydroa Vacciniforme-like T-cell Lymphoproliferative Disorder.- Adult T-cell Leukemia/Lymphoma (ATLL).- Primary Cutaneous Acral CD8+ T-cell Lymphoma (Indolent DC8+ Lymphoid Proliferation of the Ear).- Primary Cutaneous Peripheral T-cell Lymphoma, Unspecified.- Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type.- Primary Cutaneous Diffuse Large B-cell Lymphoma, Other.- Primary Cutaneous Follicle Center Lymphoma.- Primary Cutaneous Marginal Zone B-cell Lymphoma.- Lymphomatoid Granulomatosis (LYG).- Blastic Plasmacytoid Dendritic Cell Neoplasm.- Appendices.
Antonio Subtil, MD, MBABoard Certified, Dermatopathology and HematopathologyAssociate Professor, Dermatology and PathologyYale University School of MedicineNew Haven, CTUSA