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This book collects the revised selected proceedings of the First International Symposium in Molecular Logic and Computational Synthetic Biology ( MLCSB), held in Chile, Santiago, in December 2018. The volume contains 7 full revised papers along with 2 surveys from 19 submissions presented at the symposium. One of the goals of the MLCSB 2018 was to explore the potential of molecular logic frameworks to study the emerging behavioural patterns in biological networks, combining discrete, continuous and stochastic features, and resorting both to specific or general-purpose analysis and verification techniques.

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Molecular Logic: Brief Introduction and Some Philosophical Considerations.- Verification for everyone? An overview of Dynamic Logic.- Oscillatory behaviour on a non-autonomous hybrid SIR-model.- Combinatorial dynamics for regulatory networks.- Reactive models for biological regulatory networks.- Temporal Logic Based Synthesis of Experimentally Constrained Interaction Networks.- On the existence of synergies and the separability of closed reaction networks.- A Logical Framework for Modelling Breast Cancer Progression.- Random chromatin neighborhoods in 2n=40 Mus m. domesticus meiotic cells: P-percolation and image segmentation.

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