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This volume provides a concise yet comprehensive overview of precancerous lesions and gynecologic tract cancers. Each section discusses the historic evolution of a precancerous lesion, its epidemiology, the nature of the published evidence that supports its characterization as a precancerous lesion, and gives a detailed description of morphologic, immunophenotypic and molecular properties, and patient outcomes. The volume also features 2 separate chapters on the clinical management of precancerous lesions of the gynecologic tract as a well as the cytopathology of cervical precancerous lesions.

Lavishly illustrated and written by some of the foremost experts in the field, Precancerous Lesions of the Gynecologic Tract: Diagnostic and Molecular Genetic Pathology is a definitive account of precancerous lesions of the gynecologic tract and is a valuable resource for pathologists, oncologists, and gynecologists.

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Section I: Ovary, Fallopian Tube and Peritoneum

1. Precursors of High Grade Serous Carcinoma

Patricia A. Shaw, Blaise Clarke, Sophia HL George

2. Precursors of Low Grade Serous Adenocarcinoma of the Ovary: Pathology and Molecular Pathways

Kate Lawrenson, Paulette Mhawech-Fauceglia

3. Precancerous lesions of ovarian clear cell and endometrioid carcinomas

Andres A. Roma

4. Clinical Management of Selected Precancerous Lesions of the Uterus, Fallopian Tube, and Ovary

Xiaomang B. Stickles

Section II: Uterine Corpus

5. Putative Precursor Lesions of Gestational Trophoblastic Neoplasia

Natalia Buza and Pei Hui

6. Putative precursors of Uterine Sarcomas

Qing Zhang, Jian-Jun Wei

7. Precancerous Lesions of Endometrioid Adenocarcinoma

Susanne K. Jeffus, Charles M. Quick

8. Precancerous lesions of endometrial serous carcinomas

Oluwole Fadare, Wenxin Zheng

Section III: Uterine Cervix, Vulva and Vagina

9. Vulvar Intrapithelial Neoplasia

Demaretta S. Rush, Edward J. Wilkinson
10. Vaginal Intraepithelial Neoplasia

Philip P.C. Ip, Ka Yu TSE

11. Cytology of Cervical Precancerous Lesions

Zaibo Li, Chengquan Zhao

12. Precursors of Cervical Adenocarcinomas

Yoshiki Mikami, Atsumi Kojima

13. Precancerous lesions of squamous cell carcinoma of the cervix: squamous dysplasia

Lynn Hirschowitz, Simon Herrington

14. Clinical Management of Selected Precancerous Lesions

in the Lower Genital Tract

Hironori Tashiro, Hidetaka Katabuchi

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"The intent is to provide a comprehensive overview of precancerous lesions of the gynecologic tract. This book serves practicing pathologists, pathology fellows, and pathology residents. It is also an invaluable resource for academic researchers, clinical colleagues (especially gynecologists), gynecology residents, as well as oncologists. ... Overall, this is a practical, succinctly written, and well-illustrated book. ... It should be widely distributed to pathology and general hospital libraries." (Shuying Ji, Doody´s Book Reviews, May, 2016)

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Oluwole Fadare, MD
Professor of Pathology, Director of Surgical Pathology, University of California San Diego, Department of Pathology, San Diego, CA, USA

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