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This book discusses normal sex-related differences in lung structure and function and the role these differences play in lung disease. New research on the effects of sex hormone signaling on specific cell types of the lung has begun to reveal how these hormones may drive or prevent lung disease. Expertly written chapters examine the effects of sex hormones on normal pulmonary structure and function, hormone signaling in lung health, and specific diseases such as chronic obstructive pulmonary disease, asthma, pulmonary hypertension, and lung cancer. Gender, Sex Hormones, and Respiratory Disease: A Comprehensive Guide focuses on our current understanding and the gaps in research, with suggestions for future directions and implications for therapy. This book is a useful reference for pulmonologists and researchers and will prompt further inquiry aimed at improving overall lung health.

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Introduction.- 1.Sex Differences in Normal Pulmonary Structure and Function at Rest and during Exercise.- 2.Sex Hormone Signaling In The Lung In Health And Disease: Airways, Parenchyma And Pulmonary Vasculature.- 3.Women and COPD.- 4.Sex, gender, and asthma.- 5.Sex hormones, sex, gender and pulmonary hypertension.- 6.Pulmonary Fibrosis.- 7.Sex-Specific Differences in Lung Cancer.- 8.Lymphangioleiomyomatosis.- 9.Developmental Lung Disease.

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Dr. Anna R. Hemnes received her undergraduate degree from Columbia University in 1995 and her M.D. from Johns Hopkins in 1999. She completed her Internal Medicine residency and fellowship in Pulmonary and Critical Care Medicine at Johns Hopkins as well. She received advanced training in pulmonary vascular disease at Vanderbilt and has incorporated this interest into her research focus: physiology of pulmonary vascular disease. Her laboratory investigates how the right ventricle hypertrophies and fails in the load stress of pulmonary hypertension and the influence of gender on this phenotype. She is also interested in the non-invasive diagnosis and evaluation of pulmonary vascular disease ranging from pulmonary embolism to pulmonary arterial and venous hypertension.

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