---

The second edition of this well-received book reflects the state of the art in surgery for malignant bone tumors in children, with a particular focus on epiphysiolysis before excision. With a thorough update, new chapters, a clear presentation of tips and tricks to address complications, as well as supplementary online videos and tutorials, this book addresses the challenges of limb preservation that are posed to the surgeon in this new era of cancer treatment characterized by higher survival rates and longer survival times.

The authors are experienced practitioners of Ca¤adell´s technique, but the book also explores, thanks to the focused contributions of experts from other fields of medicine, a range of topics from the molecular biology and histological aspects of bone tumors, to the use of imaging techniques and surgical options for epiphyseal preservation.

Abundant illustrations and accounts of clinical results make this book an indispensable guide for orthopedic surgeons and pediatric oncologists and give the book an interdisciplinary appeal to practitioners in more general orthopedics, oncology, pediatrics and surgery.

---

History of surgery for limb bone tumors.- Non-Surgical Treatment Of Pediatric Bone Sarcomas.- Molecular Biology of Pediatric Bone Sarcomas.- Limb Salvage in Skeletally Immature Patients with Extremity Sarcoma.- Location of Sarcomas Within Bone: The Growth Plate.- A Histological Study of the Barrier Effect of the Physis Against Metaphyseal Osteosarcoma.- Growth Plate Involvement in Malignant Bone Tumours: Relationship Between Imaging Methods and Histological Findings.- Consequences of Delayed Diagnosis.- Imaging-Based Indications for Resection with Epiphyseal Preservation.- Conservation of the Epiphysis While Removing Metaphyseal Bone Tumors: Epiphysiolysis Before Excision.- Complications of the technique and solutions.- Clinical Results.- Other Techniques for Epiphyseal Preservation.- Worldwide Experience with the Ca¤adell Technique.- Questions and Answers.

---

"A review of the recent advances in the treatment of malignant bone disease. ... The 14 chapters contain many illustrations, partly in color, and many references. Recommended to orthopedic surgeons and oncologists." (Pediatric Endocrinology Reviews (PER), Vol. 13 (4), June, 2016)

"The audience is practicing orthopedic oncologists who regularly treat young patients with bone sarcomas. ... offers a concise and interesting overview of the history of orthopedic oncology ... . The book is well illustrated and provides several case examples to help readers appreciate the thought process behind this innovative technique and clarify the situations when the experienced authors could apply epiphysiolysis to enhance the outcomes of properly selected patients. This is a very useful book for specialists in orthopedic oncology." (Yasser R. Farid, Doody´s Book Reviews, May, 2016)

---

MIKEL SAN-JULIAN MD, PhD

Associate Professor

DEPARTMENT of ORTHOPAEDIC SURGERY

UNIVERSITY OF NAVARRA

PAMPLONA

NAVARRA



SPAIN

---