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In this book a new innovative approach was introduced, namely to develop functional gp 120-liposome conjugates which enable vaccination by the intrastructural help strategy. The main goal was the covalent conjugation of the HIV envelope protein gp 120 (UFO) to liposomes. The aimed covalent conjugation should be formed between UFO and 16:0 Dodecanoyl PE-, respectively DSPE-PEG14-COOH- functionalised liposomes using the activation chemicals EDC/sulfo-NHS. Liposomes were prepared and processed, followed by a physicochemical and chemical characterization of protein. Furthermore liposome-protein conjugates were processed and characterized.

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Kohlhauser, Bianca
Bianca Kohlhauser, M.Sc. developed her passion for biochemistry after completing her bachelor´s degree in Nutrition Science and an internship at the Fraunhofer Institute. To complete her master program Biological Chemistry at the University of Vienna she performed her master thesis in cooperation with Polymun Scientific and the BOKU Vienna

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