## Neuerscheinungen 2009Stand: 2019-05-06 |
Schnellsuche
ISBN/Stichwort/Autor |
Herderstraße 10 10625 Berlin Tel.: 030 315 714 16 Fax 030 315 714 14 info@buchspektrum.de |

2009. 88 S.

Verlag/Jahr: VDM VERLAG DR. MÜLLER 2009

ISBN: 3-639-13153-3 (3639131533)

Neue ISBN: 978-3-639-13153-6 (9783639131536)

Preis und Lieferzeit: Bitte klicken

A deep and analytical understanding of the human

metabolism grabbed attention of scientists from

biology, medicine and pharmacy. Mathematical models

of metabolic pathways offer several advances for

this deep and analytical understanding due to their

incompensable potential in predicting metabolic

processes and anticipating appropriate interventions

when required. This book concerns mathematical

modelling analysis and simulation of metabolic

pathways. These pathways include intracellular and

extracellular compounds such as enzymes,

metabolites, nucleotides and cofactors. The

mathematical models are either in the form of

nonlinear ordinary differential equations (ODE´s) or

differential algebraic equations (DAE´s). These

equations are composed of kinetic parameters such as

kinetic rate constants, initial rates and

concentrations of metabolites. In this book, an

enzymatic system which includes Creatine Kinase,

Hexokinase and Glucose 6-Phosphate Dehydrogenase (CK-

HK-G6PDH) is modelled in the form of DAE´s, solved

numerically and the system parameters are estimated.

Dr. Süreyya Özö ür-Akyüz studied Mathematics at Middle East

Technical University (METU), Turkey. She did her Msc and PhD at

Institute of Applied Mathematics (IAM), METU. Dr. Özö ür-Akyüz

is a postdoctoral researcher at Sabanc University, Turkey where

she is working on pattern recognition, data mining and

continuous optimization.