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The aim of this book is to ground students in the basic principles of biochemistry and molecular biophysics. It delves into developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies.

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advanced undergraduate/beginning graduate level students and would be applied to courses focusing on three different areas:
Foundations of molecular biophysics
Macromolecular structure and assembly
Methods in physical biochemistry

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PART I: Principles of Biophysical Inquiry
Chapter 1 Philosophy and Practice of Biophysical Study
Chapter 2 Overview of the Biological System Under Study - Descriptive Models
Chapter 3 Physical Thoughts, Biological Systems - The application of modeling principles to understanding biological systems
Chapter 4 Probability and Statistics
PART II: Foundations
Chapter 5 Physical Principles: Energy - The Prime Observable
Chapter 6 Biophysical Forces in Molecular Systems
Chapter 7 An Introduction to Quantum Mechanics
Chapter 8 Chemical Principles
Chapter 9 Measuring the Energy of a System: Energetics and the First Law of Thermodynamics
Chapter 10 Entropy and the Second Law of Thermodynamics
Chapter 11 Which Way Did That System Go? The Gibbs Free Energy
Chapter 12 The Thermodynamics of Phase Equilibria

PART III: Building a Model of Biomolecular Structure
Chapter 13 Water: A Unique Structure, A Unique Solvent
Chapter 14 Ion-Solvent Interactions
Chapter 15 Ion-Ion Interactions
Chapter 16 Lipids in Aqueous Solution
Chapter 17 Macromolecules in Solution
Chapter 18 Molecular Modeling - Mapping Biochemical State Space
Chapter 19 The Electrified Interphase

PART IV: Function and Action Biological State Space
Chapter 20 Transport and Kinetics: Processes Not at Equilibrium
Chapter 21 Flow in a Chemical Potential Field: Diffusion
Chapter 22 Flow in an Electrical Field: Conduction
Chapter 23 Forces Across Membranes
Chapter 24 Kinetics - Chemical Kinetics
Chapter 25 Bioelectrochemistry - Charge Transfer in Biological Systems

PART V: Methods for the Measuring Structure and Function
Chapter 26 Separation and Characterization of Biomolecules Based on Macroscopic Properties
Chapter 27 Determining Structure by molecular interactions with photons: Electronic Spectroscopy
Chapter 28 Determining Structure by molecular interactions with photons: Scattering Phenomena
Chapter 29 Analysis of Structure - Microscopy

PART VI: Physical Constants
Physical Constants

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