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Rashid Minhas, Samina Shakeel (Beteiligte)

Over Expression of EMP3 Gene in Breast Carcinomal Tissue

A study conducted in Pakistani patients
2010. 64 S.
Verlag/Jahr: VDM VERLAG DR. MÜLLER 2010
ISBN: 3-639-31039-X (363931039X)
Neue ISBN: 978-3-639-31039-9 (9783639310399)

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Investigated the overexpression of EMP3 gene (a trans membrane signaling molecule with important roles in the regulation of apoptosis, differentiation and invasion of cancer cells) in freshly frozen biopsies of cancerous tissues compared to normal breast tissue using semi-quantitative PCR and Real Time PCR. Sequencing and correlation of EMP3 overexpression to various stages of breast cancer were also found.