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D. Kishore, Sumitra Nain, Sarvesh Paliwal (Beteiligte)

QSAR of pyrrolo benzodiazepine derivatives


Pyrrolo benzodiazepine as anti cancer agents
2011. 56 S.
Verlag/Jahr: VDM VERLAG DR. MÜLLER 2011
ISBN: 3-639-37784-2 (3639377842)
Neue ISBN: 978-3-639-37784-2 (9783639377842)

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Quantitative structure activity relationship studies are indubitably of great importance in modern chemistry. In pursuit of better anti-cancer agents QSAR studies were performed on a series of pyrrolo-benzodiazepine derivatives. The models were developed using training set compounds employing multiple linear regression and partial least square with many descriptors like electronic, topological, and geometrical. The developed models were evaluated for statistical significance and predictive power
Sumitra Nain has done m.pharmacy in medicinal chemistry from Rajasthan university of health sciences, Jaipur. She is working as a Assistant Professor in Banasthali University.