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New developments such as refined combined modality approaches and significant technical advances in radiation treatment planning and delivery are facilitating the re-irradiation of previously exposed volumes. As a consequence, both palliative and curative approaches can be pursued at various disease sites.
Re-irradiation: New Frontiers is the first book to provide a comprehensive overview on current re-irradiation strategies. Re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance are all discussed in detail. In addition, disease-specific chapters document recent clinical results and future research directions. Professionals involved in radiation treatment planning and multimodal oncology treatment will find this book to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

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Normal Tissue Tolerance to Re-irradiation.- A Role for Hyper- and Ultrafractionation?- Hyperthermia and Re-Irradiation.- Increased Therapeutic Ratio with Sensitizers, Cytotoxic Drugs, Targeted Agents?.- Reduced Normal Tissue Doses through Advanced Technology: IMRT, IGRT....- Brain Tumors.- Eye Tumors.- Head and Neck Cancer.- Lung Cancer.- Breast Cancer.- Prostate Cancer.- Rectal Cancer.- Gynecologic Cancer.- Sarcoma.- Bone Metastases.- Brain Metastases.- Subject Index.

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From the reviews:

"´Re-irradiation: New frontiers´ attempts to provide a comprehensive overview on current re-irradiation strategies and addresses re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, as well as normal tissue tolerance. ... In summary, this is a book which brings together the available evidence on re-irradiation, which I suspect might be useful as an occasional reference text in the hospital library ... ." (Joe O´Sullivan, RAD Magazine, February, 2012)

"This very detailed and in-depth book, will be appreciated by those working in the field, oncology radiotherapists as well as clinicians and surgeons who have to deal with this difficult medical problem." (Giampiero Beluffi, La Radiologia Medica, Vol. 118, 2013)

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