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Recent research has given great insight into the physiological and pharmaceutical effects of histamine on the central nervous system and especially on the brain. This volume focuses on these many new findings, including the role of brain histamine in the arousal system, learning, and memory. Also featured are the mechanisms of histamine release in bone marrow and mast cells and the role of histamine in neutrophil differentiation. These are analyzed using the most up-to-date techniques of molecular pharmacology and refined immunoelectroscopy. In addition, the pharmacological profiles of newly developed H1 antagonists are described, making this book invaluable to those who want to understand the very latest advances in histamine research.

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