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This practical overview of fMRI explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases.

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Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases, translating research into clinical application.

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BOLD Functional MRI.- Principles of Functional MRI.- fMRI Scanning Methodologies.- Experimental Design and Data Analysis for fMRI.- Challenges in fMRI and Its Limitations.- Clinical Challenges of fMRI.- Neuroanatomical Atlas.- Neuroanatomical Atlas.- fMRI Clinical Applications.- Brain Mapping for Neurosurgery and Cognitive Neuroscience.- Applications of fMRI to Psychiatry.- fMRI of Memory in Aging and Dementia.- fMRI of Language Systems: Methods and Applications.- fMRI Wada Test: Prospects for Presurgical Mapping of Language and Memory.- fMRI of Epilepsy.- fMRI of the Visual Pathways.- fMRI of the Auditory Cortex.- Pediatric Applications of fMRI.- fMRI of Clinical Pain.- Pharmacological Applications of fMRI.- Cognitive Neuroscience Applications.- Clinical Overview and Future fMRI Applications.

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Radiology Review:

"... The editors are respected experts in the field of MR imaging. ... Each chapter provides a substantial list of references ... The book contains a multitude of large high-resolution images, and some chapters contain informative tables that summarize and compare the literature. The book is easy to read, and the chapters on the underlying physical principles of functional MR imaging are particularly enjoyable. ... The editors achieved their goal of providing a thorough introduction to clinical functional MR imaging at a reasonable price. ..." (Birgit Kettenmann, PhD; Radiology Dec 2007)

From the reviews:

"The book is organized into 3 parts, with 19 chapters and an appendix. ... Color illustrations of fMRI mappings abound (134 full-color illustrations in all), and each chapter is extensively referenced. ... Young fMRI researchers would certainly benefit ... . The more clinically oriented reader to whom the book is ostensibly targeted can find much useful information ... ." (American Journal of Neuroradiology, Vol. 28, October, 2007)

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