---

This volume is intended for clinicians, researchers, residents, and students. The range is wide and the depth considerable for all the topics covered in the treatment of this timely and relevant subject. This book may serve equally well as a general introduction and a scholarly reference. Ultimately, it is designed to serve those patients suffering from abuse of and addiction to drugs and alcohol. The content and organization of the book flow from general concepts of abuse and addiction to specific details of the pharmacology of alcohol and drugs. Special chapters on topics not found in most other books, such as pharmacology of drug-drug interactions, abstinence, and prevention, are included. This book is written especially for the clinician interested in the pharma cology of alcohol and drugs of abuse and addiction. The pharmacology is integrated into a conceptual approach to diagnosis and treatment of alcohol and drug abuse and addiction. The form and style are didactic, critical as well as straightforward in presentation. Literature references from recent clinical research and basic research provide the foundation for the chapters throughout the book. Be cause the book is written by a clinician-researcher, the information is readily adaptable to clinical problems and research ideas. I would like to express my deep appreciation to Susan Newsom and Darlene Tucci for their invaluable technical assistance. Norman S. Miller vii Contents Preface ....................................................... vii CHAPTER 1 Introduction to the Pharmacological Effects of Alcohol and Drugs and Addiction on the Brain and Behavior .... . . . . . . . . . . . . . . . . . .. . . 1 . . . . . .

---

1 Introduction To The Pharmacological Effects Of Alcohol And Drugs And Addiction On The Brain And Behavior.- 2 The Behavioral Concepts Of Abuse And Addiction In Diagnosis.- 3 The Neurochemistry Of Tolerance, Dependence, And Addiction.- 4 Suicide In Alcoholism And Drug Addiction.- 5 The Genetics Of Alcoholism.- 6 The Medical Consequences Of Alcohol And Drugs Of Abuse And Addiction.- 7 The Psychiatric Consequences Of Alcohol And Drugs Of Abuse And Addiction.- 8 The Pharmacology Of Alcohol And Drugs And Sexual Responsivity.- 9 The Pharmacology Of Alcohol.- 10 The Pharmacology Of Amphetamines.- 11 The Pharmacology Of Anabolic-Androgen Steroids.- 12 The Pharmacology Of Benzodiazepines.- 13 The Pharmacology Of Cocaine.- 14 The Pharmacology Of Hallucinogens And Designer Drugs.- 15 The Pharmacology Of Inhalants And Volatile Solvents.- 16 The Pharmacology Of Marijuana (Cannabis).- 17 The Pharmacology Of Multiple Drug And Alcohol Addiction.- 18 The Pharmacology Of Narcotics: Natural, Semisynthetic, And Synthetic.- 19 The Pharmacology Of Nicotine.- 20 The Pharmacology Of Nonprescription Medications.- 21 The Pharmacology Of Phencyclidine.- 22 The Pharmacology Of Sedatives/Hypnotics.- 23 The Pharmacology Of Interactions Between Medical And Psychiatric Drugs.- 24 The Pharmacology Of Drug Testing: Indications And Methodology 291.- 25 The Pharmacological Treatment Of The Acute Intoxication And Detoxification Of Alcohol And Drugs Of Abuse And Addiction.- 26 The Pharmacology Of Abstinence.- 27 The Nonpharmacological Treatment Of Abuse And Addiction To Alcohol And Drugs.- 28 The Prevention Of Abuse And Addiction To Alcohol And Drugs.

---