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Revision with unchanged content. CATE enables a systematic application of computer-aided technologies, i.e., computer-aided design (CAD), image processing, computer-aided ma nu fac tu ring (CAM), and solid freeform fabrication (SFF) for modeling, designing, si mulation, and manufacturing of biological tissue and organ sub stitutes. Through the use of CATE, the design of intricate three dimensional ar chi tec ture of scaffold can be realized and these scaffolds can be fabricated with re producible accuracy to assist biologists in studying complex tissue en gi nee r ing problems. This book outlines research addressing some of the challenges in applying the CATE approach for the biomimetic design and freeform fabri cation of tissue scaffolds. CATE enables many novel approaches in modeling, design, and fabrication of complex tissue substitutes with enhanced func tio nality for research in patient specific implant analysis and simulation, image guided surgical planning and scaffold guided tissue engineering. The research will also enable cell biologists and engineers to expand their scope of re search and study in the field of tissue engineering and regenerative medicine.

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Wei Sun, Professor, Computer Aided Tissue Engineering at Drexel UniversityBinil Starly, Assistant Professor, Engineering living tissue systems at University of Oklahoma

Assistant Professor, Engineering living tissue systems at University of Oklahoma

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