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Inflammatory dieseases of the pancreas occur with increasing
incidence in western industrialized countries. This volume
deals with all aspects of CHRONIC PANCREATITIS including
epidemiology, etiology, morphology and pathophysiology, dia-
gnostic imaging as well as conservative and operative treat-
ment. Very recent data based on experimental and clinical
research projects are presented. The contributions have all
been written by a team of internationally well recognized
authorities in the various fields involved. Topics of parti-
cular interest include feed-back regulation, new aspects of
conservative and interventional treatment as well as modern
surgical approaches including organ-preserving procedures.

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´Definition - Epidemiology - Etiology.- Update in the Classification of Chronic Pancreatitis.- Incidence and Prevalence of Chronic Pancreatitis.- Role of Nutrition in Chronic Pancreatitis.- Alcohol, the Alimentary Tract and the Pancreas: Facts and Controversies.- Non-Alcohol-Related Etiologies in Chronic Pancreatitis.- Chronic Pancreatitis with Inflammatory Mass in the Head of the Pancreas: A Special Entity?.- Natural History of Chronic (Progressive) Pancreatitis: A Life Experience.- Pathophysiology.- Exocrine and Endocrine Morphologic Changes in Chronic Pancreatitis.- Focal Necrosis: Primary Event in the Pathogenesis of Chronic Pancreatitis?.- Morphology of Nerves in Chronic Pancreatitis and the Interrelationship with Inflammatory Tissue.- Peptidergic Innervation in Chronic Pancreatitis.- Is There a Link Between Chronic Pancreatitis and Pancreatic Cancer?.- Pathophysiology.- Chronic Pancreatitis: Search for Animal Models.- Pancreatic Adaptation, Growth and Regeneration in Experimental Chronic Pancreatitis.- Lysosomal Enzyme Activation of Digestive Enzymes During Chronic Pancreatitis?.- Role of Alcohol in the Development of Chronic Pancreatitis.- Fate of Pancreatic Enzymes During Gastrointestinal Transit.- The Carbon and Oxygen Isotope Composition of Pancreatic Stones.- A. Fresh Look at Autoantibodies in Chronic Pancreatitis.- Feedback Regulation of Exocrine Function.- Gastrointestinal Hormones in Chronic Pancreatitis.- Feedback Mechanisms in the Control of Exocrine Pancreatic Function.- Influence of Intestinal Protease Inhibition on Pancreatic Feedback Regulation.- Influence of Cholecystokinin - Receptor Antagonists on Feedback Regulation of Pancreatic Secretion.- Does Feedback Regulation Exist in Chronic Pancreatitis?.- Clinical Features.- Pain in Chronic Pancreatitis: Pathomechanism and Clinical Presentation.- Ductal Morphology and Pain in Chronic Alcohol-Induced Pancreatitis.- Relationship Between Function and Morphology in Chronic Pancreatitis.- Gastrointestinal Motility in Chronic Pancreatitis.- Endocrine Pancreatic Function During Atrophy of the Exocrine Gland in Rats and Patients with Chronic Pancreatitis.- Pancreas Divisum and Pancreatitis: Implications and Rationale for Treatment.- Complications.- Complications in Chronic Pancreatitis.- Clinical Relevance of Cholestasis Syndrome in Chronic Pancreatitis - The Cape Town Experience.- Pseudocysts in Chronic Pancreatitis: Development and Clinical Implications.- Pancreatic Ascites.- Diagnosis.- Role of Serum Enzymes in Chronic Pancreatitis.- Value and Clinical Role of Intubation Tests in Chronic Pancreatitis.- Value of Indirect Pancreatic Function Tests.- How to Position Exocrine and Endocrine Function Tests in the Diagnostic Approach to Chronic Pancreatitis.- Magnetic Resonance Imaging and Computed Tomography in Chronic Pancreatitis.- Role of ERCP in Chronic Pancreatitis.- Imaging of Chronic Pancreatitis: A Synopsis.- Conservative Treatment.- The Role of Analgesic Treatment in Chronic Pancreatitis.- Modern Treatment of Exocrine Pancreatic Insufficiency.- Enzyme Supplementation for Pain in Chronic Pancreatitis.- Diabetes Mellitus in Chronic Pancreatitis.- Interventional Treatment.- Direct Cholangiopancreatoscopy and Use of Pancreatic Duct Stents and Drains in the Treatment of Pancreatitis.- Nonoperative Management of Pancreatic Pseudocysts: Selective Expectant Management.- Nonoperative Management of Chronic Pancreatic Pseudocysts.- Surgical Treatment: Indication.- Indications for Surgical Treatment in Chronic Pancreatitis.- Reducing the Risk of Pancreatic Surgery.- Surgical Treatment: Denervation and Drainage.- Denervation Procedures in the Management of Chronic Pancreatitis.- Why and When to Drain the Pancreatic Ductal System.- Pseudocyst Drainage in Chronic Pancreatitis.- Operative Therapy of Pancreatic Pseudocysts.- What Type of Pseudocyst Should Undergo Surgery?.- Pancrea

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