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Kewal K. Jain

The Handbook of Biomarkers


2010. 2014. xx, 492 S. 41 Tabellen. 235 mm
Verlag/Jahr: SPRINGER, BERLIN; HUMANA PRESS 2014
ISBN: 1-62703-836-1 (1627038361)
Neue ISBN: 978-1-62703-836-2 (9781627038362)

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This handbook describes many different types of biomarkers and their discovery. It also presents the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials.
Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain´s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers.

Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.
ook fulfills the need for a single, comprehensive guide through the discovery, validation, and application of various biomarkers." (Rachel Renee Chennault, Doody´s Review Service, July, 2010)