Nematodes are cosmopolitan and found everywhere in every animal as parasite and harm a lot , if we work out on its molecular study than we can easily find out its root for destroying it. Students get everything on the nematodes of Meerut region and they got interesting studies and also they inspire to do a lot on it and can easily carry forward the research with various wide interesting parameters. In this study Nematodes acts as Biological Control over the Cockroaches population. And the study shows the Biological Significance of Nematodes.It helps in natural eradication of cockroaches.Dr. Sangeeta Pal did her research on Periplaneta americana of Meerut region in U.P. and tried to find out the biological significance of cockroach. Molecular work was also done to evaluate the phylogenetic relationships between them and made the work easy and interesting. Thanks for appreciation and promotion.