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Hon Pong (Gary) Ho
Fasciculography
Volumetric Tract Parcellation from Diffusion Magnetic Resonance Images
2014. 184 S. 220 mm
Verlag/Jahr: SCHOLAR´S PRESS 2014
ISBN: 3-639-70255-7 (3639702557)
Neue ISBN: 978-3-639-70255-2 (9783639702552)
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White matter parcellation from Diffusion Magnetic Resonance Images reveals detailed 3D white matter structure and connectivity of the brain in vivo and thus is a viable tool for investigating neural differences. Measurements derived from these neural tracts or fascicles from Diffusion Tensor Images (DTI) exhibit potential as biomarkers for neurologic and neuropsychiatric disorders. - - - - - - - - - - - - - - - - - - - - We develop and implement a parcellation method that aims for lower sensitivity to initialization and local orientation error by directly segmenting full white matter tracts, rather than reconstructing individual curves, from diffusion tensor fields. A fast, robust volumetric and intrinsically normalized solution is achieved by efficient sampling and noise-filtering using a generic parametrized tract model. Interactive tract modification schemes are also developed to resolve ambiguity in branching tracts or to perform regional investigation for long fascicles.
Hon Pong (Gary) Ho has been working on medical and computer vision problems since 1999. He received his PhD of Biomedical Engineering from Yale University in 2011. He has been a senior software engineer at Intel Perceptual Computing in California, USA since 2011, leading R&D of real time interactive computer vision solutions.