---

This volume presents the conception and prototype realization of a self-powered architecture for subcutaneous detector devices. The architecture is designed to work as a threshold-level alarm of substances detected through a three-electrodes amperometric BioSensor approach.

---

A CMOS Self-Powered Front-End Architecture for Subcutaneous Event-Detector Devices presents the conception and prototype realization of a Self-Powered architecture for subcutaneous detector devices. The architecture is designed to work as a true/false (event detector) or threshold level alarm of some substances, ions, etc... that are detected through a three-electrodes amperometric BioSensor approach. The device is envisaged as a Low-Power subcutaneous implantable application powered by an inductive link, one emitter antenna at the external side of the skin and the receiver antenna under the skin.

The sensor is controlled with a Potentiostat circuit and then, a post-processing unit detects the desired levels and activates the transmission via a backscattering method by the inductive link. All the instrumentation, except the power module, is implemented in the so called BioChip. Following the idea of the powering link to harvest energy of the magnetic induced link at the implanted device, a Multi-Harvesting Power Chip (MHPC) has been also designed.

---

Preface / Abstract. Abbreviations.

1 Introduction. 1.1 Energy Harvesting in Human and Non-Human Activities. 1.2 BioSensors. 1.3 Circuits for Three Electrodes BioSensors. 1.4 Contribution of this Book. 1.5 Outline of the Book. 1.6 References.

2 Energy Harvesting (Multi Harvesting Power Chip). 2.1 Multi Harvesting Power Chip (MHPC). 2.2 Solar and Inductive Power Harvesting. 2.3 Piezoelectric Harvesting. 2.4 Chapter Conclusions. 2.5 References.

3 Biomedical Integrated Instrumentation. 3.1 General Introduction to Biomedical Instrumentation. 3.2 Electrochemical Biosensors. 3.3 Potentiostat (Sensor Instrumentation). 3.4. Low-Frequency Lock-In Amplifier. 3.5 Biotelemetry for Implanted Devices. 3.6 Chapter Conclusions. 3.7 References.

4 CMOS Front-End Architecture for In-Vivo Biomedical Subcutaneous Detection Devices. 4.1 Introduction. 4.2 Front-End General Architecture. 4.3 Prototypes Design and Results. 4.4 Chapter Conclusions. 4.5 References.

5 Conclusions and Future Work. 5.1 Conclusions. 5.2 Future Work.

Appendix 1. Appendix 2. Appendix 3.

---