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developed. When I did not identify European colleagues In this rapidly evolving field it is appropriate to update frequently our state of the art knowledge of uremia therapy. who had the expertise who could expend the time and with Hence, this third edition of Replacement of Renal Function whom I could work so smoothly, I began alone. by Dialysis appears before many of its predecessors have Although I was tempted to ask all the same authors as had been destroyed by normal wear and tear over 11 and 6 years written so well previously to contribute again, I realized that the new edition must be revitalized. Accordingly a fraction of use, respectively. The first two editions of this book were designed to be of the authors changed, some new topics have been added integrated comprehensive reviews of the pertinent aspects and others have been deleted. The multinational character of dialysis and related fields with sufficient clarity for the of authorship has been maintained. Existing chapters have novice to learn, yet adequate depth for the expert to rely on been rewritten thoroughly, and new authors have provided them as encyclopedic desk references on renal replacement as requested a full discussion and bibliography in keeping therapy. Based on the favorable readers´ comments and with the previous editions.

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1. Introduction.- 2. Uremic toxicity.- 3. Haemodialysis: a historical review.- 4. Principles and biophysics of dialysis.- 5. Dialysers.- 6. Membranes for extracorporeal therapy.- 7.Pretreatment and preparation of city water for hemodialysis.- 8. The composition of dialysis fluid.- 9. Angioaccess in the renal failure patient.- 10. Extracorporeal thrombogenesis: mechanisms and prevention.- 11. Practical use of anticoagulants.- 12. Hemodialysis monitors and monitoring.- 13. Biophysics of ultrafiltration and hemofiltration.- 14. Ultrafiltration and hemofiltration, practical applications.- 15. Continuous arteriovenous hemofiltration (CAVH) and other continuous replacement therapies: operational characteristics and clinical use.- 16. Short treatment.- 17. Single needle haemodialysis.- 18. Multiple use of hemodialyzers.- 19. Dialysate regeneration.- 20. Hemoperfusion.- 21. Plasma exchange: principles and practice.- 22. Peritoneal dialysis: a historical review.- 23. Peritoneal anatomy and transport physiology.- 24. Practical use of peritoneal dialysis.- 25. Continuous ambulatory peritoneal dialysis.- 26. Acute renal failure.- 27. Planning, developing and operating a dialysis programme.- 28. Patient selection and integration of renal replacement therapy.- 29. Regular dialysis treatment.- 30. Home hemodialysis.- 31. International review of renal replacement therapy: strategies and results.- 32. Renal replacement therapy in children.- 33. Acute complications associated with hemodialysis.- 34. Blood pressure control in chronic dialysis patients.- Cardiac complications of uremia and dialysis.- 36. Hyperlipidaemia and atherosclerosis in chronic dialysis patients.- 37. Acid base homeostasis in clinical dialysis.- 38. Pulmonary aspects of dialysis patients.- 39. Gastrointestinal complications of renal failure.- 40. Hematological problems of dialysis patients.- 41. Host defenses and infectious complications in maintenance hemodialysis patients.- 42. Dialysis associated hepatitis.- 43. Dialysis in the acquired immunodeficiency syndrome.- 44. Renal osteodystrophy and maintenance dialysis.- 45. Endocrine changes in chronic dialysis patients.- 46. Neurological aspects of dialysis patients.- 47. Ophthalmological complications associated with haemodialysis.- 48. Oral aspects of renal failure.- 49. Trace elements and regular dialysis.- 50. Aluminium toxicity in renal failure.- 51. Pharmacological considerations for renal failure and dialysis.- 52. Anaesthesia and major surgery in patients with renal failure.- 53. Nutrition in dialysis patients.- 54. Management of the uremic diabetic patient.- 55. Prevention of renal failure.- 56. Prolonged survival on hemodialysis.- 57. Social, ethical, and legal issues involved in chronic maintenance dialysis.

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