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Written in a clear and understandable manner, this book provides a comprehensive, yet non-mathematical, treatment of the topic, covering the basic principles of symmetry and the important spectroscopic techniques used to probe molecular structure.
The chapters are extensively illustrated and deal with such topics as symmetry elements, operations and descriptors, symmetry guidelines, high-fidelity pseudosymmetry, crystallographic symmetry, molecular gears, and experimental techniques, including X-ray crystallography and NMR spectroscopy. As an additional feature, 3D animations of most of the structures and molecules covered are available online at wiley.com. As a result, chemists learn how to understand and predict molecular structures and reactivity.
Authored by a renowned expert with numerous publications and an excellent track record in research and teaching, this is a useful source for graduate students and researchers working in the field of organic synthesis, physical chemistry, biochemistry, and crystallography, while equally serving as supplementary reading for courses on stereochemistry, organic synthesis, or crystallography.

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Symmetry/Pseudosymmetry; Chirality in Molecules, Nature, and in the Cosmos
Enantiospecificity of Pheromones, Sweetners, Fragrances, and in Drug Discovery
Bonding Parameters and the Effect of Local Environment upon Molecular Structure
Historical Development of Structural Chemistry: From Alchemy to Modern Structural Theory
Chrioptical Properties
Symmetry Comparison of Molecular Subunits: Symmetry in Nuclear Magnetic Resonance Spectroscopy and in Dynamic NMR
Prochirality, Asymmetric Hydrogenation Reactions and the Curtin-Hammett Principle
Stereogenic Elements, Chirotopicity, Permutational Ismers, and Gear-Like Correlated Motion of Molecular Subunits
Symmetry in Extended Periodic Arrays of Molecular Crystals, and the Relevance of Pensrose Tiling Rules for Non-Periodic Quazicrystal Packing
Multiple Molecules in the Asymmetric Unit, ´Faking It´; Pseudosymmetry Emulation of Achiral Higher Order Space Filling in Kryptoracemate Chiral Crystals
Platonic-Solid Geometry Molecules and Crystallographic Constraints upon Molecular Geometry, Symmetry Distortions from Ideality
Solid-State NMR Spectroscopy/X-Ray Crystallographic Investigation of Conformational Polymorphism/Pseudopolymorphism in Crystalline Stable and Labile Hydrated Drugs
NMR Spectroscopic Differentiation of Diastereomeric Isomers Having Special Positions of Molecular Symmetry
Stereochemistry of Medium Ring Conformations
The Pharmacophore Method
The X-Ray Structure-Based Method of Rational Design
Helical Stereochemistry
Index

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