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Haralampos M. Moutsopoulos, Manuel Ramos-Casals, John H. Stone (Beteiligte)

Sjögren´s Syndrome


Diagnosis and Therapeutics
Herausgegeben von Ramos-Casals, Manuel; Stone, John H.; Moutsopoulos, Haralampos M.
Softcover reprint of the original 1st ed. 2012. 2016. xx, 633 S. 235 mm
Verlag/Jahr: SPRINGER, BERLIN; SPRINGER, LONDON; SPRINGER 2016
ISBN: 1-447-17146-2 (1447171462)
Neue ISBN: 978-1-447-17146-1 (9781447171461)

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This thorough overview of the clinical manifestations of SS has specific chapters dedicated to each organ involved, a user-friendly device ensuring coverage of all medical specialties and facilitating speedy assessment of the symptoms SS patients present.
Sjögren´s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren´s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren´s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist.
In addition to being a diagnostic guide, Sjögren´s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren´s Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques.
The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms.
Epidemiology.- Genetics and Proteomics.- Immunopathogenesis.- Viruses.- Etiopathogenic role of B-cells.- Oral involvement.- Ocular involvement.- Ear, nose and throat involvement.- Fatigue, fibromyalgia and other general symptoms.- Musculoskeletal involvement.- Non-vasculitic cutaneous involvement.- Vasculitis.- Cardiovascular involvement.- Pulmonary involvement.- Raynaud phenomenon.- Gastrointestinal involvement.- Autoimmune liver involvement.- Pancreatic involvement.- Nephro-urological involvement.- Central nervous system involvement.- Peripheral neuropathy.- Autonomic neuropathy.- Endocrine involvement.- Gynecological and obstetrical complications.- Laboratory abnormalities.- Diagnostic procedures (I).- Diagnostic procedures (II).- Immunological tests.- Classification criteria.- Measurement of chronicity and activity.- Measurement of quality of life.- Association with other autoimmune and rheumatic diseases.- Cancer.- Prognostic factors and survival.- SS in primary care.-Treatment of sicca features.- Treatment of B-cell lymphoma.- Classic immunosuppressive and immunomodulatory drugs.- New immunosuppressive and immunomodulatory drugs.- B-cell targeted therapies.- Other biological therapies.- Experimental therapies.
From the reviews:

"This is a detailed examination of Sjogren´s syndrome, from pathogenesis to diagnosis and treatment of the disease. One of the book´s greatest strengths is its utility as a reference. ... appropriate for students, residents, and practitioners, but especially for practicing rheumatologists. ... the book is quite enjoyable and easy to read cover-to-cover. The writing is clear and the subject is covered thoroughly. ... This is probably the most outstanding, authoritative book on the subject that I have encountered. Any rheumatologist could benefit from reading it." (Jonathan Miner, Doody´s Review Service, February, 2013)