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The undisputed gold standard text in the field, Ryan´s Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan´s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training.

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Part I: Retinal Imaging and Diagnostics

1. Fluorescein Angiography: Basic Principles and Interpretation

2. Clinical Applications of Diagnostic Indocyanine Green Angiography

3. Optical Coherence Tomography

4. Autofluorescence Imaging

5. Widefield Imaging

6. Intraoperative OCT Imaging

7. Advanced Imaging Technologies

8. Advanced Image Analysis

9. Electrogenesis of the Electroretinogram

10. Clinical Electrophysiology

11. Diagnostic Ophthalmic Ultrasound

12. Color Vision and Night Vision

13. Visual Acuity and Contrast Sensitivity

14. Visual Fields in Retinal Disease

Part 2: Basic Science and Translation to Therapy

Section 1: Anatomy and Physiology

15. The Development of the Retina

16. Structure and Function of Rod and Cone Photoreceptors

17. Function and Anatomy of the Mammalian Retina

18. Cell Biology of the Retinal Pigment Epithelium

19. Cell Biology of Retinal Glia

20. Retinal and Choroidal Vasculature: Retinal Oxygenation

21. Mechanisms of Normal Retinal Adhesion

22. Structure, Function, and Pathology of Bruch´s Membrane

23. Vitreous and Vitreoretinal Interface

Section 2: Basic Mechanisms of Injury in the Retina

24. Mechanisms of Oxidative Stress in Retinal Injury

25. Mechanisms of Endoplasmic Reticulum Stress in Retinal Disease

26. Cell Death, Apoptosis, and Autophagy in Retinal Injury

27. Inflammation and Immune Responses In Retinal Health and Disease

28. Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis

29. Blood-Retinal Barrier, Immune Privilege, and Autoimmunity

30. Mechanisms of Macular Edema and Therapeutic Approaches

31. Cellular Effects of Detachment and Reattachment on the Neural Retina and the Retinal Pigment Epithelium

32. Pathogenesis of Serous Detachment of the Retina and Pigment Epithelium

Section 3: Genetics

33. Genetic Mechanisms of Retinal Disease

34. Mitochondrial Genetics of Retinal Disease

35. Epigenetic Mechanisms of Retinal Disease

Section 4: Translational Basic Science

36. Gene Therapy for Retinal Disease

37. Stem Cells and Cellular Therapy

38. Nanomedicine in Ophthalmology

39. Neuroprotection

40. Drug Delivery

41. Retinal Laser Therapy: Biophysical Basis and Applications

Medical Retina

Section 1: Retinal Degenerations and Dystrophies

42. Retinitis Pigmentosa and Allied Disorders

43. Hereditary Vitreoretinal Degenerations

44. Macular Dystrophies

45. Hereditary Choroidal Diseases

46. Abnormalities of Cone and Rod Function

Section 2: Retinal Vascular Disease

47. The Epidemiology of Diabetic Retinopathy

48. Diabetic Retinopathy: Genetics and Etiologic Mechanisms

49. Medical Management of Diabetes Mellitus

50. Nonproliferative Diabetic Retinopathy and Diabetic Macular Edema

51. Proliferative Diabetic Retinopathy

52. Hypertension

53. Telescreening for Diabetic Retinopathy

54. Retinal Artery Occlusions

55. Acquired Retinal Macroaneurysms

56. Branch Vein Occlusion

57. Central Retinal Vein Occlusion

58. Macular Telangiectasia

59. Coats Disease

60. Hemoglobinopathies

61. Radiation Retinopathy

62. Ocular Ischemic Syndrome

63. Coagulopathies

64. Pediatric Retinal Vascular Diseases Retinopathy of Prematurity

65. Telescreening for Retinopathy of Prematurity

Section 3: Choroidal Vascular/Bruch´s Membrane Disease

66. Epidemiology and Risk Factors for Age-Related Macular Degeneration

67. Pathogenetic Mechanisms in Age-Related Macular Degeneration

68. Age-Related Macular Degeneration: Non-neovascular Early AMD, Intermediate AMD, and Geographic Atrophy

69. Neovascular (Exudative or "Wet") Age-Related Macular Degeneration

70. Pharmacotherapy of Age-Related Macular Degeneration

71. Pathologic Myopia

72. Angioid Streaks

73. Ocular Histoplasmosis

74. Polypoidal Choroidal Vasculopathy

75. Central Serous Chorioretinopathy

76. Uveal Effusion Syndrome and Hypot

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