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Donald W. Light, Antonio F. Maturo (Beteiligte)

Good Pharma


The Public-health Model of the Mario Negri Institute
1st ed. 2015. 2017. xviii, 282 S. 31 SW-Abb. 235 mm
Verlag/Jahr: SPRINGER PALGRAVE MACMILLAN; PALGRAVE MACMILLAN US 2017
ISBN: 1-349-67840-6 (1349678406)
Neue ISBN: 978-1-349-67840-2 (9781349678402)

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Drawing on key concepts in sociology and management, this history describes a remarkable institute that has elevated medical research and worked out solutions to the troubling practices of commercial pharmaceutical research. Good Pharma is the answer to Goldacre´s Bad Pharma : ethical research without commercial distortions.
1. List of Illustrations 2. Foreword 3. Preface and Acknowledgements 4. List of Abbreviations 5. Introduction: Beneficence through Principled Research for Patients PART I: DEVELOPING A RESEARCH INSTITUTE FOR SOCIETY 6. Origins and American Inspirations 7. The Formative Years Leadership, Culture & Organization 8. Expansions to New Campuses and Integrated Research 9. Educating the Public and Future Researchers PART II: RECONCEIVING THE AIMS OF PHARMACOLOGICAL RESEARCH 10. From Measuring Environmental Toxins to Drugs as Contaminants 11. Pioneering Ethical Trials for Integrated Research PART III: PROMOTING GOOD SCIENCE FOR BETTER MEDICINES 12. Science-based Initiatives Against Dangerous or Useless Drugs 13. Global Campaigns Against Harmful Regulations and Practices 14. Good Science for Good Pharma A Global Model 15. Appendices
"Good pharma is a fascinating story and a must read for all those who believe that something is not right about the way we incentivise medical research today. Both laypersons and specialists in the field will find something to think about in a book that is full of delectable nuggets of information interspersed in the story of Silvio Garattini and the Mario Negri Institute." (Amit Sengupta, Indian Journal of Medical Ethics, August, 2016)

"By offering a sociological perspective on the drug development process, this book presents an alternative perspective to mainstream pharmaceutical drug production focused on patenting and profit while ignoring public-health needs. ... The book shows how personal life events and experiences collided to lead to the founding of the institute. ... a welcome addition to the sociology of health and medicine and would likely appeal to those interested in critical perspectives of pharmaceuticals, health and the regulation of clinical trials." (Shadreck Mwale, Sociology of Health & Illness, June, 2016)

"The authors document what they see as the generalizable best practices of this pharmacological research institution, which is based in Milan and has centers in two other Italian cities. ... Some readers may already be familiar with the litany of complaints about the pharmaceutical industry, as well as the proposed best practices chronicled in Good Pharma. Even for them, the book may be worth reading." (Jennifer E. Miller, Health Affairs, Vol. 34 (12), 2015)

"Good Pharma tells the story from 1961 to present of the origins and development of the Instituto di Ricerche Farmacologiche Mario Negri, named after its endower, a Milanese jeweller-philanthropist. ... Good Pharma is worth reading and digesting as it documents how the Negri model has produced some outstanding successes, such as the GISSI trials, and makes a strong case for viewing pharmacological research as a long-term risky investment." (Drug and Therapeutics Bulletin of Navarre, Vol. 23 (2), 2015)