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Dementia is the progressive deterioration of a largely irreversible clinical syndrome in cognitive function- the ability to process thought. It is a significant burden issue all over the world in the 21st century due to its under detection and sub-optimal management by healthcare professionals (HPs)-there is a gap in the literature as to what represents best practice with regard to educating HPs to improve their dementia detection practices and management. Therefore, misdiagnosis rate is increasing. Thus, it is far better to test early which can significantly aid in the diagnosis and management process. Neither there are no gold standards medication, diagnostic guidelines nor educational interventions for the HPs to improve their skill of diagnosis, management and care of dementia. Moreover, the GPs are the best position to diagnose dementia than other health professionals with the collaboration of nurses. On the other hand, the cancer drugs are not a miracle cure for AD- Bexarotene (chemotherapy) improves cognition and other symptoms that appear with AD patients and will be a significant drug in the coming decades.

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Dr. Krishna Prasad Pathak, is a Gerontologist, researcher, editors, and lecturer in Nepal. he is appointed as purple Angel Ambassadors UK-Nepal, 2016 committee member of "walk to end Alzheimer" in Alzheimer Association, USA, 2016 and guest editor of Journal of Behavior Therapy and Mental Health.His research interest Neurodegenerative disease.

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